Bio‐Compliant Composites: Biocompliant Composite Au/pHEMA Plasmonic Scaffolds for 3D Cell Culture and Noninvasive Sensing of Cellular Metabolites (Adv. Healthcare Mater. 4/2021)

نویسندگان

چکیده

A 3D-printable composite material consisting of gold nanoparticles embedded within a poly-2-hydroxyethylmethacrylate matrix, that serves dual functions as both host framework scaffold for pre-osteoblasts, well non-invasive plasmonic biosensor cellular metabolites, is presented in article number 2001040 by Ralph G. Nuzzo and co-workers. The 3D printing ink particle-free the are generated 3D-printed scaffolds via postprint chemical reduction method. Pre-osteoblast cells successfully grown differentiated into mature osteoblasts over printed scaffolds. Cellular metabolites detected using surface-enhanced Raman spectroscopy during different stages cell growth differentiation. Common cellular, some free amino acids, SERS demonstrating ability to function biologically compliant culture applications.

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ژورنال

عنوان ژورنال: Advanced Healthcare Materials

سال: 2021

ISSN: ['2192-2640', '2192-2659']

DOI: https://doi.org/10.1002/adhm.202170016